November ODs Hit Record Low as Manchester Continues Anti-Addiction Push
Once the epicenter of New Hampshire’s opioid crisis, Manchester continues to show signs of recovery, with a record-low number of overdoses reported in November.
According to Mayor Jay Ruais, the numbers show city efforts to address the crisis are working — and saving lives.
“Manchester’s continued decline in suspected opioid overdoses and overdose deaths shows that our coordinated, evidence-based approach is making a real difference,” Ruais said. “Being 28 percent below last year in total suspected overdoses and nearly 20 percent lower in suspected overdose deaths puts us on track for a potential record low in 2025. This progress reflects the tireless work of our first responders, public health partners and recovery organizations, and it reinforces the importance of staying focused on prevention, treatment and long-term recovery.”
Statistics reported last week by Chris Stawasz, Northeast regional director of government affairs for private ambulance service Global Medical Response Inc., show overdoses in Manchester and Nashua continue to decline.

“November’s opioid overdose response numbers were notable once again by setting another record low for the second month in a row,” Stawasz said. “That virtually assures that 2025 will have the lowest annual number of suspected opioid overdoses in a decade in both Nashua and Manchester.”
Manchester experienced 24 reported overdoses in November, slightly up from October’s 17, but still in line for a dramatic year-over-year decrease. The city is on track for the lowest overdose and overdose fatality numbers in more than a decade, according to Stawasz.
“Manchester is continuing to trend toward ending 2025 with a record-low number of annual suspected opioid overdoses and is currently 28 percent below last year in total annual suspected opioid overdoses,” Stawasz said.
Manchester recorded 345 total overdoses through the end of November and is expected to reach 377 by the end of December. Compared to 2024’s 527 total overdoses, that represents a significant decrease. Overdose-related fatalities are also down, with two reported in November. The current total of 35 overdose fatalities for the year is far below the peak of the epidemic.
When Stawasz began tracking the opioid crisis in 2015, Manchester recorded 728 overdoses and 88 deaths. It is anticipated that 2025 will end with fewer than 40 overdose fatalities.
Nashua’s opioid numbers are on a similar trajectory. The city reported seven overdoses and two overdose fatalities in November, putting it on track for 161 total overdoses by the end of the year and 25 overdose fatalities.
While Nashua’s overdose fatality total is higher than 2024’s 20 deaths, the numbers still represent a major improvement. In 2016, the city recorded 361 overdoses and 44 overdose fatalities.
Efforts such as the state’s Doorway program and the ready availability of over-the-counter Narcan have contributed to the steady decline, according to Stawasz.


